Designation: Professor
Specialization: Cancer Biology, Molecular Biology & HIV
Contact:
Email: shanju.lisam [AT] manipuruniv.ac.in
Msc, Ph.D.
Website: http://manipuruniv.ac.in/faculty/70
Lisam shanjukumar singh, Ph.D.
Professor
Cancer & molecular biology lab (CMBL).
DEPARTMENT OF BIOTECHNOLOGY,
ROOM # 204,
MANIPUR UNIVERSITY,
IMPHAL, CANCHIPUR, MANIPUR, 795003
Email: shanju.lisam@gmail.com shanju.lisam@manipuruniv.ac.in
Research team of cancer & molecular biology lab
TEAM OF CANCER & MOLECULAR BIOLOGY LAB CONDUCTING RT-PCR COVID-19 TEST AT THE TESTING CENTRES TO HELP THE MANIPUR STATE GOVERNMENT DURING COVID-19 PANDEMIC
MAIN RESEARCH OUTCOME SUMMARY:
Cancer Biology:
A new Metastasis Suppressor Gene (MSG) which as named as OGR1, was identified. Its dual opposite roles in the cancer cell and host cells of the tumour microenvironment were revealed.
A new intronless gene encoding CK2? (CSNK2A3) was identified and revealed its expression in human cells.
Further, the differential regulation of CSNK2A3 and CSNK2A1 expressions by OGR1 in cancer/tissue-specific manner was revealed. The role of CSNK2A3/CSNK2A1 and OGR1 and their molecular mechanisms in myeloid differentiation were also discovered.
Drug discovery
A novel anticancer phytochemical, Oroxyquonine, was discovered, and its molecular mechanisms for inducing apoptosis were revealed. The sensitisation activities of other phytochemicals were revealed.
HIV/AIDS
The complexity of the molecular epidemiology of HIV-1 and drug-resistant HIV-1 variants among the HIV-infected people of Manipur was revealed.
Experience
July 2022 - till date- Professor, Department of Biotechnology, Manipur University.
March 2019 to July 2022-Professor and Head, Department of Biotechnology, Manipur University
April 2015 to March 2018-Professor and Head, Department of Biotechnology, Manipur University
March 2012-April 2018-Associate Professor and Head Department of Biotechnology, Manipur University
March 2009-March 2012-Reader and Head Department of Biotechnology, Manipur University
POST-DOCTORAL EXPERIENCE:
April 2006-March 2009-Research Staff -Indiana University-Purdue University, Indianapolis, USA
Feb 2003-April 2006-Post-Doctoral Researcher, Cleveland Clinic, Ohio, USA
March 2002-Feb 2003-Post-Doctoral Researcher, Cleveland State University, Ohio, USA
April 1999-Jan 2001-Research Associate, Case Western Reserve University, Ohio, USA
Details of Honors/Awards received:
2006-Achievement for Excellence in Cancer Research, Indiana University Cancer Center.
2004-The Cleveland Clinic innovation award for “Development of a method for the inhibition of metastasis”
Details of Patents:
Devices for Rapid Single and Multiple Cell Blocks Preparative simultaneously in Visibly Low Cellular Samples, Lisam Shanjukumar Singh and Desai Fanny Sharadkumar, Published/WO2019/229508 A1 (International) 05/12/2019
Anticancer Composition, Thiyam Ramsing Singh, Lisam Shanjukumar Singh, Ch. Brajakishor Singh and Thangjam Davis Singh, Filed/TEMP/E-1/49404/2019/KOL (Intellectual Property India) 15/11/2019
Composition for the Prevention or Treatment of Mastitis, Lisam Shanjukumar Singh, T. Chanu Machathoibi and Asem Robindro Singh Filed/CBR No. 11675 (Intellectual Property India) 31/08/2021