Faculty Member: Prof L Warjeet Singh

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Designation	Professor
Specialization	Organic Chemistry
email	werjeet@yahoo.com
Highest Degree	M Sc, PhD
Honours/Awards
Research Projects
Research Papers

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A Brief Introduction

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Professor Laitonjam Warjeet Singh obtained his B.Sc (Chemistry Honors) from Gauhati University in the year 1978 and M.Sc. specializing in Organic Chemistry from North Eastern Hill University, Shillong (1981). Prof. Singh got his Ph.D. degree under the supervision of Prof. H. Junjappa, NEHU on Synthetic Organic Chemistry in 1987. He got the JRF, CSIR during 1982-1984; SRF, CSIR during 1985-1987 and RA, CSIR during 1987-1988. Joined the Department of Chemistry, Manipur University as an Assistant Professor on 14 December 1988; promoted to Reader in the year 1998 and to Professor in the year 2006. At present he is serving Head of Department in the Department of Chemistry, Manipur University since 1st September 2010.

He is a Commonwealth Fellow of Association of Commonwealth Universities, London, UK from 1-10-1997 to 30-9-1998 and worked with Prof. E.J. Thomas (Editor of Tetrahedron, Tet. Lett.), University of Manchester, U.K. in the research area of total synthesis of natural product, Pamamycin-an antibiotic.

He visited the IICB, Kolkata from 14/12/2001 to 16/01/2002 as Visiting Scientist under the NEC Programme (UGC). He was nominated by the Royal Society, London as Visiting Scientist at the University of Manchester, UK from 31/01/2006 to 05/05/2006. Visited the Department of Chemistry, NEHU, SHillong as a UGC Visiting Fellow in 1999 and 2000.

His research areas are on Development of Newer Synthetic Methods both for Heterocyclic and Carbocyclic compounds; Synthesis of Natural Products; and Chemical Studies on Medicinal Plants. Under his guidance, ten research scholars have been awarded for their Ph.D. degrees and at present, six research scholars are working.

Research Project

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• Systematic transformations and mechanistic investigations on 1,3-diarylthiobarbituric acids.
  CSIR, New Delhi ( 1/51993 - 30/4/1996)
• Problems and Management of Waste Substances in Imphal town
  DST, Govt. of Manipur (1/5/1996 - 30/4/1997)
• Synthesis of Natural Product – Pamamycin, an Antibiotic.
  Association of Commonwealth Universities,U K (1/10/1997 to 30/9/1998 )
• Chemical Investigation of traditional Dye Plant Kum of Manipur.
  DST, Govt of Manipur, (1/8/1999 to 31/7/2000)
• Chemical studies on certain medicinal plants of Manipur.
  CSIR, New Delhi, 1/6/2000 - 31/5/2003
• Study and Restoration of Traditional Dyes of Manipur and Elucidating the Structures of the Colourants.
  DST, New Delhi, (10/04/2003 - 09/04/2006)
• Antioxidants and Free Radical scavenging effects in extracts of Zingiberacea species exclusively.
  DST, New Delhi, 1/4/2004 - 31/03/2006
• Screening of plants of North-east India for Anti- cancer activities, isolation, characterization and evaluation
  ICMR, New Delhi, (01/03/2006 - 28/02/2009 )
• Isolation and Characterization of certain medicinal plants of Manipur having anti-diabetic properties
  CSIR, New Delhi, ( 1/5/2007 - 30/4/2011 )
• Development and commercialization of traditional KUM as Hair Dye.
  DST, New Delhi, (1/7/2009 - 30/6/2012 )
• Investigation on synthesis, development and applications of metal-proline complexes as organo-catalysts for organic reactions in aqueus media.
  DST, New Delhi, ( 1/12/2009 - 30/11/2012 )

Research Paper

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• A Review on Traditional medicinal plants of Manipur as Anti-diabetics
  Singh, L.W.
  J Med Plants Research, vol. 4(18), 0000 (2010)
• A new and facile synthetic approach to substituted 2-thioxoquinazolin-4-ones by the annulations of a pyridine derivative,
  Singh, L W, Nimalini, D M Beil.
  J. Org. Chem. , 6, 1056-1060, (2010)
• Studies on chemical constituents and antioxidant activities of extracts from the roots of Smilax lanceaefolia Roxb.
  Singh, L.W., Brajeshwari, D.K. Nat.
  Prod. Res., 24, 1168-1176, (2010)
• Synthesis of biologically active pyranopyrimidines.
  Singh, L.W., Nimalini. M.
  Med. Chem. Res., 19, S95, (2010)
• Enantioselective direct aldol reactions catalyzed by Cd-proline complex
  Singh, L.W., Bhavna, Th.
  Med. Chem. Res., 19, S59, (2010).
• Chromium(III)chloride catalyzed one-pot synthesis of pyrimidine-2-thiones from arylidines and thioureas.
  Singh, L W, Nimalini D Moirangthem
  Ind. J. Chem., 48B, 1023-1026, (2009)
• Isolation and antimicrobial studies of the compounds isolated from the stem bark of Ficus hispida Linn. Singh, L.W., Bimola D. Asem,
  Asian J. Chem., 20 (8), 6027-6032, (2008).
• Natural dye yielding plants and indigenous knowledge of dyeing in Manipur, Northeast India.
  Singh, L.W., Lunalisa, P., Swapana, N.
  Ind. J. Trad. Know. , 7(1),141-147,(2008).
• Antifungal and phytochemical studies of Eupatorium birmanicum DC
  Singh, L.W., Devi, L.R., Singh, Th.S.
  Ind. J. Chem., 46B, 1868. (2007).
• Antioxidant properties of some exclusive species of Zingiberaceae family of Manipur
  Singh, L.W.; Vankar, P.S.; Tiwari, V.; Swapana, N.
  Electronic J. Env. Agri. and Food Chem. (Spain),, 1318-1322, 2006.
• A facile synthesis of steroidal pyrazoles, isoxazoles and pyrimidines from testosterone.
  Singh, L.W.; Singh, Ch. B.
  Ind. J. Chem. 2006, 45B, 959-966, (2006).
• Synthesis of fused pyrazolo-, isoxazolo-, pyrimido-, and pyrido-pyrimidines
  Singh, L. W.; Thokchom, H.; Devi, N.A.
  Canadian Journal of Chemistry 2005, 83(8), 1056-1062., (2005).
• Sterols and flavonol glycosides from Melothria purpusila.
  Singh, L.W.; Devi, L.R.; Devi, K. B.
  Ind. J. Chem., 44B, 1291-1294, (2005).
• Synthesis of some A- and D-ring fused steroidal pyrazoles, isoxazoles and pyrimidines.
  Singh, L.W.; Tombisana, R.K.; Singh, C.B.
  Steroids 2002, 67, 203-209, (2002).
• Stereocontrolled syntheses of 2,5-disubstituted tetrahydrofurans using remote asymmetric induction
  Singh, L.W.; Hobson, L.A.; Thomas,
  E.J. Arkivoc 2001, Vol. 2, part 10, U46, 2001.
• Synthesis of pyrazolo[3,2-c]cholest4-ene derivatives from cholesterol.
  Singh, L.W.; Tombisana, R.K.
  Ind. J. Chem. , 38B, 847-849, 1999.
• Synthesis of pyrimido[4,3-d]pyrimidines as antifungal agents
  Singh, L.W.; Devi, N.A.; Tombisana, R.K.; Khuman, C.K.
  Ind. J. Heterocycl. Chem., 7, 193-196, 1998.
• Synthesis of substituted 4-oxo- and substituted ,3-dihydro-4-oxo-isoxazolo[5,4-d]-pyrimidin-6-thiones
  Singh, L.W.; Devi, N.A.
  Ind. J. Chem., 35B, 478-479, (1996).
• A facile synthesis of 2,3-dihydro-3,5,7-triphenyl- and 2,3-dihydro-3-phenyl-5,7-diaryl-4-oxo-pyrazolo[3,4-d]pyrimidin-6-thiones.
  Singh, L.W.; Devi, N.A.
  Ind. J. Heterocycl. Chem., 5, 139-140, 1995
• Highly diastereoselective anionic[3+2]annulation strategy for functionalized cyclopentenes via a-oxoketene dithioacetals.
  Singh, L.W.; Reddy, K.R.; Ila, H.; Junjappa, H.
  J. Chem. Soc. Perkin Trans. I. , 2439-2442.1994.
• Synthesis of substituted 4-oxopyrazolo[3,4-d]pyrimidin-6-thiones from 1,3-diaryl-5-ethoxymethylene-2-thiobarbituric acids.
  Singh, L.W.; Devi, N.A.
  Ind. J. Chem. , 33B, 1091-1092.1994
• Synthesis of base catalysed reaction of 3-bis(methylthio)methylene-4-oxo-4-aryl-butene nitriles.
  Singh, L.W.; Ila, H.; Junjappa, H.
  J. Chem. Soc. Perkin Trans.I , 2365-2368, (1988).
• Synthesis of novel 6-aryl-5-(bismethylthio)methyl-3-oxo-2,3-dihydropyridazines
  Singh, L.W.; Ila, H.; Junjappa, H.
  Synthesis , 89-90. (1988).
• Reaction of cinnamoyl and 4-phenylbutadienyl ketene dithioacetals with cyanoacetamide and synthesis of novel substituted 2(H)-pyridones
  Singh, L.W.; Ila, H.; Junjappa, H.
  Ind. J. Chem. 1987, 26B, 607-610.
• A facile synthesis of 2-aryl-6-methylthio-4H-pyran-4-ones and a novel cycloaromatization reaction
  Singh, L.W.; Ila, H.; Junjappa, H.
  Synthesis 1987, 873-875.
• A facile synthesis of 6-amino-2-methylthio-4H-thiopyran-4-ones
  Singh, L.W.; Ila, H.; Junjappa, H.
  Synthesis 1985, 531-533.
• A facile synthesis of 2-amino-4-alkoxy-6-styryl- and 2-amino-4-alkoxy-6-(4-aryl-1,3-butadienyl)-pyrimidines by direct cyclocondensations
  Singh, L.W.; Gupta, A.K.; Ila, H.; Junjappa,
  H. Synthesis 1984, 516-518.
• Partial reductive demethylation of a-ketoketene S,S-acetals with sodium borohydride and nickel chloride: A new general method for 2-methylthio-1-alkenyl ketones
  Singh, L.W.; Myrboh, B.; Ila, H.; Junjappa, H.
  Synthesis 1982, 30, 307-309.