Year of Establishment

 2009

Programs Offered

M.Sc. Biotechnology (Five-Year Integrated)

Ph.D

Lisam Shanjukumar Singh, Ph.D

Associate Professor & Head

Email shanju_lisam@hotmail.com, Phone: (0385)-2435233 (O);(0385)-2435134 (R); 9615533300/9612907406 (M)

Research interest areas                        

Tumour Metastasis, Molecular Epidemiology of virus, Ageing & Development, and Blood Coagulation

Publications

1: Li H, Wang D, Singh LS, Berk M, Tan H, Zhao Z, Steinmetz R, Kirmani K, Wei G, Xu Y. Abnormalities in osteoclastogenesis and decreased tumorigenesis in mice deficient for ovarian cancer G protein-coupled receptor 1. PLoS One. 2009 May 28;4(5):e5705.

2: Singh LS, Berk M, Oates R, Zhao Z, Tan H, Jiang Y, Zhou A, Kirmani K, Steinmetz R, Lindner D, Xu Y. Ovarian cancer G protein-coupled receptor 1, a new  metastasis suppressor gene in prostate cancer. J Natl Cancer Inst. 2007. 5;99(17):1313-27.

3: Xu. Y,. Sengupta. S,. Singh. L.S., and Rosemary, S.  Novel lipid Signaling pathways in ovarian cancer cells  (Review) Cellscience (Review) 2006 Vol. 3 (1)

4: Zaslavsky A, Singh LS, Tan H, Ding H, Liang Z, Xu Y. Homo- and hetero-dimerization of LPA/S1P receptors, OGR1 and GPR4. Biochim Biophys Acta (BBA). 2006 Oct;1761(10):1200-12.

5: Ren J, Xiao YJ, Singh LS, Zhao X, Zhao Z, Feng L, Rose TM, Prestwich GD, Xu Y. Lysophosphatidic acid is constitutively produced by human peritoneal mesothelial cells and enhances adhesion, migration, and invasion of ovarian cancer cells. Cancer Res. 2006 Mar 15;66(6):3006-14.

6: Jiang Y, Berk M, Singh LS, Tan H, Yin L, Powell CT, Xu Y. KiSS1 suppresses metastasis in human ovarian cancer via inhibition of protein kinase C alpha. Clin Exp Metastasis. 2005;22(5):369-76.

7: Beck DO, Bukys MA, Singh LS, Szabo KA, Kalafatis M. The contribution of amino acid region ASP695-TYR698 of factor V to procofactor activation and factor Va function. J Biol Chem. 2004 Jan 23;279(4):3084-95.

8: Singh LS, Bukys MA, Beck DO, Kalafatis M. Amino acids Glu323, Tyr324, Glu330,  and Val331 of factor Va heavy chain are essential for expression of cofactor activity. J Biol Chem. 2003 Jul 25;278(30):28335-45.

9: Singh LS, Kalafatis M. Sequencing of full-length cDNA encoding the alpha and beta subunits of human casein kinase II from human platelets and megakaryocytic cells. Expression of the casein kinase IIalpha intronless gene in a megakaryocytic cell line. Biochemistry. 2002 Jul 16;41(28):8935-40.

10: Singh LS, Sharma R. Purification and characterization of intestinal adenosine deaminase from mice. Mol Cell Biochem. 2000 Jan; 204(1-2):127-34.

11: Singh LS, Sharma R. Alloxan diabetes regulates adenosine deaminase activity in mice: tissue- and age-specific correlation. Biochem Mol Biol Int. 1998

12. Singh, L. S. and Sharma, R.   Developmental and hormonal regulation of intestinal adenosine deaminase in mice   J Biochem. Mol.Bio. & Biophy. 1997. 1(2), 125-132.

13: Singh LS, Sharma R. Developmental expression and corticosterone inhibition of adenosine deaminase activity in different tissues of mice. Mech Ageing Dev. 1995 

Keithellakpam Sanatombi, Ph.D

Assistant Professor

Email: ksanatombi@rediffmail.com, Phone: 9856133838

Research interest areas                       

In vitro production of secondary metabolites and molecular profiling of Medicinal and Aromatic plants

Publications

1. Sanatombi, K., and Sharma, G.J. (2006). In vitro regeneration and mass multiplication of Capsicum annuum L. Journal of Food Agriculture & Environment, 4(1): 205-208.
2. Sanatombi, K., and Sharma, G.J. (2007). Micropropagation of Capsicum frutescens L. using axillary shoot explants, Scientia Horticulturae, 113(1): 96-99.
3. Sanatombi K. & Sharma G.J.(2007). Micropropagation of Capsicum annuum L. Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 35(1):57-64.
4. Sanatombi K. & Sharma G.J.(2008). In vitro plant regeneration in six cultivars of Capsicum spp. using different explants. Biologia Plantarum, 52(1): 141-145.
5. Sanatombi K. & Sharma G.J. (2008). In vitro propagation of Capsicum chinense Jacq. Biologia Plantarum, 52 (3): 517-520.
6. Sanatombi K. & Sharma G.J.(2008). Capsaicin content and pungency of different Capsicum spp. cultivars. Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 36(2):88-90.
7. Sanatombi K., S. Sen-Mandi & Sharma G.J. (2010). DNA profiling of Capsicum landraces of Manipur. Scientia Horticulturae, 124: 405–408.

Reena Haobam, Ph.D

Assistant Professor

Email: reena_haobam@rediffmail.com, Phone: 9862288063

Research interest areas                    

Embryonic Stem Cell Biology and Neurobiology

Publications

1.       Haobam R, Sindhu KM, Chandra G, Mohanakumar KP. Swim-test as a function of motor impairment in MPTP model of Parkinson’s disease: a comparative study with two mouse strains. Behav Brain Res, 163(2), 159-167, 2005.

2.       Mehta H, Haobam R, Usha R, Mohanakumar KP. Evidence for the involvement of central serotoninergic mechanisms in cholinergic tremor induced by tacrine in Balb/c mice. Behav Brain Res, 163(2), 227-236, 2005.

Takhellambam Chanu Machathoibi

Assistant Professor

Email: machathoibi2008@gmail.com, Phone: 9612709370

Research interest areas                       

Cancer Genomics, Recombinant DNA technology

Publications

Thiyam David Singh, Ph.D

Guest Lecturer

Email: davidthiyam@yahoo.co.in, Phone: 09856089778(M)

Research interest areas      

Spectroscopy and  coordination  compound of lanthanides.

Publications

1.         “Comparison of Energy Interaction Parameters for the Complexation of Pr(III) with Glutathione Reduced(GSH) in Absence and Presence of Zn(II) in  Aqueous and Aquated Organic Solvents Using 4f-4f Transition Spectra as PROBE” Th. David Singh, Ch. Sumitra, N. Yaiphaba, H. Debecca Devi, M.  Indira Devi  and N. Rajmuhon Singh, Spectrochimica Acta, 61(6)(2005)1219.

2.         Calculation of Electric Dipole Intensity Parameter to Explore Some of the Interaction Between Hard Metal Ions Pr(III) and Nd(III) with -electron Density of Butane-1,4 and Butyne-1,4-diols in Non-aqueous Solutions :An Absorption Spectral Study. Th. David Singh, Ch. Sumitra, G.C. Bag, M. Indira Devi and N. Rajmuhon Singh, Spectrochimica Acta, , 63(2006)154.

3.         Calculation of Electric Dipole Intensity Parameters of 4f-4f Transitions of  Pr(III) and Glutathione  Reduced (GSH) Complex in Presence and Absence of Zn(II). Ch. Sumitra, Th. David Singh, M. Indira Devi and N. Rajmuhon Singh, Spectrochimica Acta, Part A, 66 (2007) 1333-1339

4.         Absorption Spectral Studies of 4f-4f Transitions for the Complexation of Pr(III) and Nd(III) with Glutathione Reduced (GSH) in Presence of Zn(II) in Different Aquated Organic Solvents and Kinetics for the Complexation of Pr(III):GSH with Zn(II) to give appropriate meaning. Ch. Sumitra, Th. David Singh, M. Indira Devi and N. Rajmuhon Singh, Journal of Alloys and Compounds, 451 (2008)365-371.

5.         Computation of Energy Interaction Parameters as well as Electric Dipole intensity parameters for the absorption spectral study of the interaction of Pr(III) with LPhenylalanine, L- Glycine, L- Alanine and L- Aspartic Acid in presence and absence of Ca2+ in Organic Solvents. T. Moaienla, Th. David Singh, N. Rajmuhon Singh and  M. Indira Devi, Spectrochimica Acta (A), 74 (2009) 434.

6.         Calculation and Comparison of Energy Interaction and Intensity Parameters for the Interaction of Nd(III) with DL-Valine, DL-Alanine and β-Alanine in Presence and Absence of Ca²⁺/Zn²⁺ in Aqueous and Different Aquated Organic Solvents Using 4f-4f Transition Spectra as Probe. H. Debecca Devi,Ch. Sumitra, Th. David Singh, N. Yaiphaba, N. Mohondas Singh  and N. Rajmuhon Singh, International Journal of Spectroscopy, Vol. 2009, 9 pages

7.          Simultaneous Interaction of Two Dissimilar Metal Ions Praseodymium(III) and a Soft Metal Ion Zn(II) or a Hard Metal Ion Ca(II) with Tripeptide Glutathione (Reduced) in Different Aquated Organic Solvents : An Absorption Spectral Study. Th. David Singh, N. Mohondas Singh, N. Yaiphaba, H. Debecca Devi, Ch. Sumitra.,T. Kriyananda, M. Indira Devi and N. Rajmuhon Singh, Chem. & Environ. Res, 12(3&4)(2003)295

8.          An Absorption Spectral Study of 4f-4f Transitions for the Interaction of Pr(III) with Different Amino Acids in Aqueous and  Aquated Organic Solvents. H. Debecca Devi, Th. David Singh, N. Yaiphaba, Ch. Sumitra , M. Indira Devi and N. Rajmuhon Singh, Asian Journal of Chemistry,16(1)(2004)412

9.         Spectral Study of the Complexation of Nd(III) with Glutathione Reduced (GSH) in the Presence and Absence of Zn(II) in Aquated Organic Solvents Th. David Singh, Ch. Sumitra, N. Rajmuhon Singh and M. Indira Devi

Journal of Chemical Sciences,116(6) (2004)303.

10.        “Comparison of  Electric–Dipole Intensity Parameter for a Series of Structurally Related Pr(III) Complexes with Ureas and Thioureas in Non-aqueous Media” Th. David Singh, Ch. Sumitra, N. Rajmuhon Singh and M. Indira Devi, Asian Journal of Chemistry, 17(3) (2005) 1435.

11.        Comparison of Energy Interaction Parameters for the Complexation of Pr(III) with 1,10-Phenanthroline and 2,2^/- Bipyridyl in Different  Organic Solvents Using 4f-4f Transition Spectra as Probe : An Absorption Spectral Study. N. Yaiphaba, Th. David Singh,  Ch. Sumitra, M. Indira Devi and  N. Rajmuhon Singh, Journal Curr. Sci.,  9(2) (2006) 509-516.

12.        Comparison of Energy Interaction Parameters for the Complexation of Pr(III) with Guanosine in Absence and Presence of Zn(II) in Aqueous and Aquated Organic Solvents using 4f-4f Transition Spectra as Probe.

T.K. Singh, Th. David. Singh, N. Yaiphaba , Ch. Sumitra and N.R. Singh, Journal Curr. Sci., 10(1) (2007) 121-130.

13.        Calculation of Energy Interaction Parameters for the Complexation of Pr(III) and Nd(III) with 1,10 Phenanthroline and 2,2^/- Bipyridyl by 4f-4f Absorption Spectral Analysis. N. Yaiphaba, Th. David Singh, M. Indira Devi and N. Rajmuhon Singh, Asian Journal of Chemistry, 20(2) (2008) 901-914.

14.        Ion Pair Formation and Thermodynamics of Glycine Bis-1-Amidino-O-Methylurea Cobalt(III) Halides in Water + Methanol Mixed Solvents at Different Temperatures. N. Mohondas Singh, Th. David Singh, N. Yaiphaba and N. Rajmuhon Singh Asian Journal Of Chemistry, 20(3) (2008), 1750-1760.

15.        Conductometric Studies of the Ion Association of α -Alanine Bis-Biguanide Cobalt(III) Iodide and β-Alanine Bis-Biguanide Cobalt(III) Iodide in Methanol+ Water Mixtures at Different Temperatures

N. Mohondas Singh, Th. David Singh, G.C. Bag and  N. Rajmuhon Singh, Asian Journal of Chemistry, 21(6) (2009) 4215-4223.

16.        Ion Pair Association Constant of Bis-1-amidino-O-methylurea Copper(II) Acetate in Aqueous Medium at Different Temperature  : A Conductance Study, Gopal Chandra Bag, Th. David Singh, N. Mohondas Singh and N. Rajmuhon Singh, Asian Journal of Chemistry, 21(6) (2009) 4167-4172.

17.        An Absorption Spectral Analysis of 4f-4f Transitions to Explore the Comparison of Energy Interaction Parameters and Electric Dipole Intensity Prameters for the Complexation of Pr(III) With D-Proline and DL-Proline. Ch. Victory Devi, Th. David Singh and N. Rajmuhon Singh, Indian J. Chem. Soc., 86 (2009) 1-4.

18.        Conductometric Studies on Temperature Dependence and Thermodynamics of Ion-Association of Leucinato Bis (biguanide) Cobalt(III) Complexes. L. Sanahal Singh, Th. David Singh, N. Yaiphaba  and N. Rajmuhon Singh, Asian Journal of Chemistry, 21(8) (2009)1-4.

19.        Traditional Knowledge and Natural Dyeing System of Manipur – with Special Reference to Kum Dye N. Rajendro Singh, N. Yaiphaba, Th. David, R.K. Babita, Ch. Bino and N. Rajmuhon Singh, Indian Journal of Traditional Knowledge, 8(1) (2009)84-88.